The amendments to Section 2 (changes to the amended and amended loan agreement) of this amendment contract No. 2 are effective and the amended and amended loan contract is amended accordingly, from the date the agent received all documents listed in item 3 (previous conditions) satisfactory to the agent. Amendment agreement of April 2, 2008 by pharmAthene, Inc., PharmAthene UK Limited and PharmAthene US Corporation and Avecia Investments Limited, Avecia Biologics Limited and Avecia Biologics, Inc.10.1 Master Services Agreement of April 2, 2008, from and between PharmAthene UK Limited and Avecia Biologics Limited-99.1 April 2, 2008 press release announcing the completion of the acquisition of The Vaccine Business of Avecia. , which must be submitted by amendment. Words replaced by paragraph 8 of the 1994 amendment. . The terms and definitions used in this Amendment No. 2 contract have the same meaning as in the amended and amended loan agreement, unless otherwise stated.